Not including genderless poeple like rimuru
Medaka Kurokami from Medaka Box

pretty much as close as you're going to get to a god
https://anilist.co/character/121561/Altair
vsbattle: Tier: At least Low 7-C | At least Low 2-C
I mean just look at that character description
The next one is a spoiler for
KADO The Right Answer
https://anilist.co/character/146088/Saraka-Tsukai
she is quite literally a god with a vsbattle tier of 1-B
for comparsion saitama has a tier of
Tier: At least High 6-A, likely higher | 9-B
(lower the number the more powerful)
So, like, the most powerful female anime character? I'd say my best guesses would be:
Alice from SAO Alicization is pretty powerful. By the second arc she is the strongest "good" character, probably only seconded by Kirito (but we do not know this for sure due to certain reasons).
Sword Art Online Alicization
I think Sakura from Naruto. This may get me a lot of hate depending on who thinks Sakura is useless but I think as she develops during the series her personality changes from someone who's selfish and cynical to someone who actually wants to do better. She actually becomes very strong and potentially in terms of sheer strength the strongest character in Naruto.