It could be a negative change or a positive change.
Ex) Ending of Devilman Crybaby. It's what reaffirmed to me that it was something I saw as good.
Definitely the "Whatever happens, happens" from Spike in cowboy bebop.
Potential spoilers: The fact that everything around him was going to shit considering he was pretty much going to die while still maintaining his composure and casually smoking really showed me that this show has such a unique vibe and deserves to be talked about as one of the greats
