As much as I love both of these, I have to disagree on these points. While yes, both of them have some good comedy and heartwarming moments, for the most part I cried a lot and then felt depressed as hell; they certainly didn't cheer me up, quite the contrary.
That being said, I'm not the only person in the universe, so yeah, YMMV. :)
Don't really like to get into such discussions, but I can't for the life of me understand why people praise these two:
Berserk
Neon Genesis Evangelion
I mean, I'm fine if someone does sincerely love it, but that popular? Nah.
Nope, I won't show any mercy. ;3
Clannad After Story
Kanon 2006
Air
ef A Tale of Melodies
Plastic Memories
EDIT: These two are already in your list.