Having just binged it, it's simple and it's shallow, but the art is vibrant and lively. The humor is cute if repetitive, but I found that in most usages, it was more helpful in tying the show together than distracting from the show's progress. I think the length of the show both in episode count and episode length helped in that regard by keeping the story moving forward. Cute and quirky little fantasy comedy, wholesome and wholly enjoyable, if a bit forgettable.

If you just want to feel sadness, do resume Oyasumi Punpun. It just doesn't stop hitting.
Oyasumi Punpun
The manga for Koe to Katachi was also really good. I haven't watched the movie yet (which I see you have), but just in case you might be interested in also reading it.
Koe no Katachi
Some anime that don't seem to be on your list:
Ano Hi Mita Hana no Namae wo Bokutachi wa Mada Shiranai
Angel Beats

I had forgotten about that story... Curse you.

R402

What a mood

I don't know about my singular favorite, but each of the four songs for Yuru Camp are probably in the top ten for me.
S1 OP "Shiny Days" - Asaka

S1 ED "Fuyubiyori" (ふゆびより) - Eri Sasaki

S2 OP "Seize the Day" - Asaka

S2 ED "Harunotonari" (はるのとなり) - Eri Sasaki

"Lost in Paradise" is indeed the name of the first ending song for Jujutsu Kaisen. It's such a bop

Yotsuba 100x yes.

Currently, non-existent. I've had an SO, crushes, and some other closer relationships in the past, but eh, at this point, it's mostly on me for not really putting myself out there. Though, mild anxiety (general and social) plays a role for sure, but also there's a portion of sheer apathy. Being single is pretty freeing overall.

Megumi Katou from Saekano please and thanks
Saenai Heroine no Sodatekata

Flying Witch

It's just a very well executed slice of life; full of happy feels and perfect for just relaxing after something taxing. The manga is fantastic in that regard too.

Kami nomi zo Shiru Sekai

Not quite what I was thinking. But I guess it fits.

I was thinking more crab, snail, monkey, snake, and cat.

A couple suggestions
Acchi Kocchi
AChannel

Talking heads and head tilts: the anime. Also, paranormal activity.